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KMID : 0357920140480060413
Korean Journal of Pathology
2014 Volume.48 No. 6 p.413 ~ p.417
Myoepithelial Carcinoma of Soft Tissue: A Case Report and Review of the Literature
Choi Chang-Hwan

Chu Young-Chae
Kim Lucia
Choi Suk-Jin
Park In-Suh
Han Jee-Young
Kim Joon-Mee
Abstract
Myoepithelial carcinoma of soft tissue is extremely rare although its counterpart of the salivary gland is relatively common
and well-known with similar morphology. The histogenesis of myoepithelial carcinoma of soft tissue is still unknown. In
fact, the tumor may present with myoepithelial differentiation but not originate from myoepithelial cells.1 The tumor cells are heterogeneous in terms of cell type and architecture. The tumor cells may be epithelioid, spindled, clear, or plasmacytoid. The growth pattern varies and can be solid sheets, reticular, or trabecular architecture without ductal differentiation.2 Myoepithelial carcinoma usually shows cytologic atypia, mitotic activity, infiltrative growth, or tumor necrosis.2 Only few studies have been reported because of the rarity of myoepithelial carcinoma of soft tissue.1-4 Consequently the clinical and pathologic characterization has been limited. Also, the limitation of definite
diagnostic criteria and prognostic parameters makes the diagnosis and management of myoepithelial carcinoma of soft tissue difficult. Here we report the first case of myoepithelial carcinoma of soft tissue in Korea.
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